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Usually this is done by a doctor... But, if you have a small blister that you just can't stand anymore, you can get rid of it by following these simple steps:
1. Find a pin and drop it in a small bit of alcohol to sterilize it.
2. Puncture the blister in two separate places, and press lightly on the blister to push the fluid out.
3. Wash the blister with soap and water, applying antibiotic cream, and covering it with gauze. Let the blister heal.
4. Don't tamper with it unless you really want an infection.